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One child on placebo was unblinded and removed from the study because of a potential serious adverse event

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Which is scientifically legitimate for hypothesis generation but insufficient for clinical recommendations

Copper is also a much-needed compound in many enzymatic and cell reactions in the body

For GSTs, the protective role toward cytotoxicity or mutagenicity has been shown for many xenobiotics, including environmental carcinogens, such as polycyclic aromatic hydrocarbons (Tashiro et al., 2001) and cisplatin (Peklak-Scott et al., 2008), and hepatotoxic drugs such as diclofenac (Tolosa et al., 2017)