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Increase in the level of blood glucose and hyperinsulinemia are known to cause neuronal death followed by neurodegeneration as seen with AD (Zhao and Townsend, 2009)

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10.1016/j.exer.2015.04.004 [DOI] [PMC free article] [PubMed] [Google Scholar] 6.Daley, R., Maddipatla, V., Ghosh, S., Chowdhury, O., Hose, S., Zigler, J