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An analysis of the symptoms associated with specific genes unique to RD revealed that, compared to the common genetic targets, the unique gene expression of RD affects a distinct set of clinical presentations

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All mortality rates have been standardised for age and calendar period by calculating the number of deaths that would have been expected in each five year age group and each calendar year in each smoking category if the smoking habit had had no effect on mortality, summing the corresponding observed and expected numbers, and multiplying the ratio of the two numbers by the total death rate for the ages and period covered