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J Cutan Pathol 47(10):954-959, 2020

Mechanisms of overcoming intrinsic resistance to gemcitabine in pancreatic ductal adenocarcinoma through the redox modulation

Mechanistically, AC increases toll-like receptor 4 (TLR4) expression, activates the myeloid differentiation primary response 88 (MyD88) axis, and reduces NF-B mRNA levels, but shows no toxic effects on normal cells (Daneshforouz et al