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ROS are continuously shaped byand shape in returnreactive nitrogen species (RNS), reactive sulfur species (RSS) and iron-centered chemistry (Cortese-Krott et al

The majority of studies exhibited low risk of bias across most domains, supporting the reliability of their findings

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DFP was used in several clinical trials on PD [179,180,181], AD [182, 183], FRDA [184, 185], PKAN [186,187,188], and NF [106], with only a few cases of positive clinical outcomes [106, 184]