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Telomeres are particularly sensitive to shortening under conditions of oxidative stress 61

Haanen J, Ernstoff MS, Wang Y, Menzies AM, Puzanov I, Grivas P, et al

Subsequently, they found that capsaicin can effectively inhibit the expression of vascular endothelial inflammatory mediators in both STZ-induced diabetic rats with diabetic retinopathy and human retinal microvascular endothelial cells exposed to high glucose

FIGURE 5 3.3 Sex differences and ECD Epidemiological studies indicate that although both men and women are susceptible to AS, men are more prone to developing ECD and AS when they are young