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Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition

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Prompted by a national flood insurance program that encouraged them to build in vulnerable areas, residents built closer and closer to the bayou that carries floodwater away from the reservoirs and out to the Gulf of Mexico