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Small-molecule PROTACS: new approaches to protein degradation

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Our results showed that elevated levels of GSTA2 protein could facilitate the normal liver cells and HCC cells to compensate their ROS level in responding to H 2 O 2 -induced oxidative stress, therefore, protected them against the H 2 O 2 -induced apoptosis and death

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Astrocytes and activated microglia release pro-inflammatory cytokines (TNF-, IL-1, IL-6), contributing to neuronal loss

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