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A committee responsible for the justification of whether the event is considered VOC or not was formed by the investigators (Fatma Ebeid, Sara Mekkya, Nihal Hussien)

Guerini M, Condr G, Friuli V, Maggi L, Perugini P (2022) n-acetylcysteine (NAC) and its role in clinical practice management of cystic fibrosis (CF): a review

Conclusion: This study combined network pharmacology and molecular docking to predict the underlying mechanism of Loganin against PMOP, validated by the in vivo mouse model showing that Loganin attenuated OVX-induced bone loss by inhibiting inflammation

Silymarin shows various biological activities in scientific investigations that are currently being further researched: Antioxidant: Protects cells against oxidative stress caused by free radicals Hepatoprotective: Under experimental conditions, silymarin can inhibit the binding of certain liver toxins to liver cells and support the regenerative capacity of hepatocytes Anti-inflammatory: Anti-inflammatory properties demonstrated in cell models Cholagogue: Possible support for bile production and bile flow Lipid profile: Influence on cholesterol and fat metabolism parameters in clinical studies Immunomodulatory: Activity in the immune system demonstrated in animal models Milk Thistle and the Liver Supporting liver health is the most thoroughly researched area of application for milk thistle extract

Material and methods : The study was a multicenter, pragmatic, stepped-wedge cluster-randomized trial