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low cysteine, low GSH, and/or an impaired Nrf2 response) exhibit a higher level of NLRP3-mediated inflammasome activation in response to provocative stimuli and particularly in response to adjuvanted vaccines, which are known to promote NLRP3 activity

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[Abstract] Immunofluorescence staining of BrdU, and PCNA shows proliferation of epidermal cells in mice in control, IMQ, IMQ+GSH, and IMQ+BSO(2 mg/kg, s.c., 7 d) groups

These results suggest that KMT2B may promote iron death by activating the TNF-/RFK/NOX2 signaling pathway

Nicotinamide prevents apolipoprotein B-Containing lipoprotein oxidation, inflammation and atherosclerosis in apolipoprotein E-Deficient mice