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The British Dietetic Association recommends 10 mcg daily or 2,000 mcg weekly supplements, as absorption efficiency decreases with higher single doses

Therefore, in previous reports, the prognosis of these two types was examined collectively, and age, tumor diameter, and the number of vascular invasions were cited as risk factors for recurrence [141, 143-145]

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However, this simultaneously allows time for hypoxic cells to reoxygenate and any remaining tumor cells to proliferate, reducing the clinical outcome of both treatments (Saggar and Tannock, 2015)