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The refinement was carried out in several cycles of automated refinement in phenix.refine program [43] and manual model building performed in Coot [44]

Methods: Male Wistar rats were subjected to a chow (CHOW) diet or a free-choice (fc) diet of either chow, saturated fat and liquid sugar (fcHFHS), chow and saturated fat (fcHF), or chow and liquid sugar (fcHS) for 4 weeks

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This helps maintain receptor sensitivity and ensures long-term effectiveness

This review summarizes the mechanisms by which MPs exposure induces gut microbiota dysbiosis and skin damage from an integrated gutskin axis perspective, highlighting their interplays relevance