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As a result, blocking the antioxidant defense in tumors decreases their ability to balance oxidative stress and results in cell death [61]

Following data acquisition, images were prepared using flexImaging software (version 4.1, Bruker Daltonics GmbH, Bremen, Germany)

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In humans, the prevalence of developing cancer-associated cachexia ranges from 31 to 87% (5759), and in 20% of cases it is the main cause of death (59)