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High-throughput screening in MADD cell lines has identified several lumichrome derivatives that restore mutant ETFDH activity at micromolar concentrations, validating the concept of pharmacological riboflavin agonists (76)

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Many cells remaining to protect creating larger therapeutic window

Mol Vis 18:26732686 Rosemberg DB, da Rocha RF, Rico EP, Zanotto-Filho A, Dias RD, Bogo MR, Bonan CD, Moreira JCF, Klamt F, Souza DO (2010) Taurine prevents enhancement of acetylcholinesterase activity induced by acute ethanol exposure and decreases the level of markers of oxidative stress in zebrafish brain

2.3.6 Number Stroop task Participants would see numbers with 14 ciphers (where each cipher was the same number, which could be 1, 2, 3, or 4, e.g., 22, 3, 444)