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PubMed Central, Liew, Winnie-Pui-Pui, and Sabran Mohd-Redzwan

(c) nuclear translocation of predominantly p65/p50 dimers to induce transcription of target genes, including well-established FLICE-like inhibitory protein (c-FLIP) and apoptosis protein inhibitors (c-IAP)

doi: 10.34133/RESEARCH.0382

Combining, for example, a mild laser with antioxidant serums and topical agents addresses pigment production, distribution, and skin resilience simultaneously