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Interplay among metabolism, epigenetic modifications, and gene expression in cancer

(PubMed) Liao F, Folsom AR, Brancati FL

UVRAG contains an aminoterminal prolinerich sequence followed by a potential calciumdependent phospholipid binding C2 domain, a central Beclin 1binding coiledcoil domain and a carboxyterminal region

Multiple mechanisms underlie defective insulin secretion associated with -cell dysfunction ( 2+ ) storage ( in vivo for therapeutic opportunities and in vitro during direct differentiation protocols to generate totally functional hPSC-derived pancreatic -cells for diabetes therapy and drug screening