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Description

Nitrogen source activates TOR (target of rapamycin) complex 1 via glutamine and independently of Gtr/Rag proteins

Recent studies have found that BRAF/ERK inhibitors can release the feedback inhibition of upstream RTK and RAS signals, and the liberation of RTK and RAS signals can facilitate other signalling pathways, such as the PI3K/AKT/mTORC1 pathway, which improves cell growth and proliferation 181