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High blood sugar makes hemoglobin bind to glucose, reducing oxygen to tissues

It acts by competitively occupying the GnRH receptors, thus reducing the level of estrogen and progesterone

Zygote 28 , 360366 (2020)

In terms of mechanism research, SchB upregulated the protein and mRNA expression levels of Nrf2, HO-1, and GPX4 in myocardial tissues of diabetic mice