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Lead-exposed workers demonstrated a 32% decrease in sperm DNA integrity (P 0.05)

Mischoulon D, Zajecka J, Freeman MP, Fava M

Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle

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1.Biosynthesis of Eicosanoids Eicosanoids are synthesized through the enzymatic oxidation of polyunsaturated fatty acids (PUFAs), primarily arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)