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It is thought that genetic, epigenetic, and environmental factors each play a role, but the exact nature of this relationship is still being explored

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Dermatologic & Tissue Health: Limited exploratory studies have looked at skin elasticity, morphologic changes, and general tissue-integrity markers in aging cohorts

1 REIMAGINE 2 was a 68-week phase 3 trial evaluating the safety and efficacy of CagriSema in doses 2.4 mg/2.4 mg and 1 mg/1 mg once weekly versus semaglutide 2.4 mg, semaglutide 1 mg, cagrilintide 2.4 mg, and dose-matched placebo in 2,713 adults with T2D inadequately controlled with metformin with or without an SGLT2 inhibitor