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Intramuscular hydroxocobalamin is the preferred treatment for most patients with confirmed deficiency, particularly when malabsorption is present or neurological symptoms exist

In one study suggesting a genetic link to poor ability to convert T4 to T3, a polymorphism in the DIO2 gene was found to be linked to who will or wont respond well to T4 therapy (due to how well their body converts T4 to T3)

b , As in a , Quantification of PMA-induced NETs in WT and XKR8-deficient dHL-60 cells with inhibitors HC067047 (1 M), Pyr3 (5 M), SKF96365 (20 M), 9-phenanthrol (30 M), JNJ-28583113 (10 M), Carvacrol (100 g/mL) ( n = 8)

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TSH: 0.45-4.5 U/ml