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Vitamin B 12 levels affect the histone modification H3K36me3, which suppresses illegitimate transcription outside of gene promoters

doi: 10.1111/bcp.13897

Omdat het van nature onderdeel is van de huid, wordt het goed verdragen door alle huidtypen, inclusief acne-gevoelige en gevoelige huid

This effect is attributed to the S-sulfhydration of SIRT1 by H 2 S, which increases its zinc binding, thereby promoting its stability and deacetylation activity (Calabrese and Scuto, 2020)