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While invasive methods are not currently considered clinically practical for the assessment of airway remodeling in asthma and obesity, non-invasive approaches such as the evaluation of CT scans and biomarkers are emerging as potential tools for predicting airway remodeling in these conditions

Al-Ghadban, S., Isern, S

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Metformin, an AMP-activated protein kinase (AMPK) activator widely used in diabetes, is currently in phase I clinical trials for heart failure with preserved ejection fraction (HFpEF) (Tables 1 and 2)