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There are seven known mammalian isoforms of NOX, including the constitutively active NOX4, along with NOX1-3, which require cytosolic subunit association for function [63]

The indicated LBD domains were expressed ectopically using lentiviruses

Sections were stained with hematoxylin and eosin and photomicrographed with a digital color camera (Cyber-Shot DSC W-230, 4X optical zoom, Sony, Tokyo, Japan) attached to an optical microscope (Leica QWin Plus-Leica Microsystems, Nussloch - Germany)

This result suggests that, even in older individuals, the lens has the capacity to reverse oxidative damage to the components of the nucleus

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