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Science 216 , 7577 (1982)

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For NAC, increases in antioxidant capacity can occur within hours to days, though improvements in liver function, respiratory health, or detoxification may take several weeks

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Although functionalized NPs with particular ligands successfully target drugs, their extremely small size and high surface area may lead to issues like particle aggregation, interparticular friction, low drug loading and high clearance rates that make them unsuitable for use in diagnosis and drug delivery