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By reducing the levels of these hydroperoxides, GPX4 inhibits the formation of more reactive and damaging lipid radicals, particularly protecting cells with membranes rich in PUFAs, which are highly susceptible to peroxidation (143,146)

Parametric and non-parametric data were analyzed using one-way ANOVA with Tukeys post hoc test or using Kruskal-Wallis analysis with Dunns post hoc test, respectively, using Prism v.9.00 (GraphPad Software, San Diego, CA, USA)

Subchronic oral toxicity of di-n-octyl phthalate and di (2-ethylhexyl) phthalate in the rat

These cells release various bioactive factors, such as cytokines, growth factors, and exosomes, which together facilitate tissue repair and regulate the immune system

Chemical space as a source for new drugs