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Senescent cells accumulate over time, and a periodic clearance is often more effective than constant exposure

Akhtar RA, Reddy AB, Maywood ES, Clayton JD, King VM, Smith AG, Gant TW, Hastings MH, Kyriacou CP (2002) Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus

Kavita U

Jung H, Chung PJ, Park SH, Redillas MCFR, Kim YS, Suh JW, Kim JK (2017) Overexpression of OsERF48 causes regulation of OsCML16 , a calmodulin-like protein gene that enhances root growth and drought tolerance