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For simulation of typical profiles at steady state, mean parameter values are shown in Table 2 for the subset of the clinical pharmacology population who used the recommended dosing conditions for oral semaglutide ( N = 209 healthy subjects, N = 55 subjects with T2D)

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Cagrilintide's safety profile from Phase 3 (REDEFINE 1) showed: GI adverse events (nausea 44%, vomiting 24%, diarrhea 20%) comparable to semaglutide alone