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Ibez, B., Heusch, G., Ovize, M., & de Van Werf, F

Beyond NTR and cathepsins, other tumor-associated enzymes have also been exploited

Glycopeptide hydrogels are typically designed through dynamic crosslinking, using dynamic covalent bonds or non-covalent interactions to confer the material with self-healing properties, excellent viscoelasticity, and adaptability to complex environments

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Notably, adding a mGluR2/3 antagonist was suggested to inhibit the action of spadin, pointing towards a dependency of spadin on mPFC TREK-1 channels that are possibly linked to mGluR2/3 receptors