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Choose too little and lower starting doses become impossibly tiny draws that are hard to measure accurately

Ilic et al., 2011a

Mouse models can provide information to support causation of EDS when an association exists in only a small number of patients

One aspect of the invention pertains to the administration of one or more NNMT inhibitors by, for example, contacting one or more cells of an animal to: (a) treat and/or prevent muscular disorders, including, but not limited to, sarcopenia, muscle atrophy, Duchenne muscular dystrophy, Becker muscular dystrophy, Limb-girdle muscular dystrophies, Pompe disease, cardiac myopathies, pulmonary disorders

Collaboration between large research groups and clinicians is key to the safe and successful progression of cartilage regeneration therapy, with the ultimate goal of providing all patients who have a cartilage injury with the opportunity for repair to conserve their joint rather than replace it