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Materials and Methods Chemicals All chemicals and reagents used in this study were of molecular and analytical grade and were purchased from Sigma Chemical Co

A letter to Clinical Toxicology from Shah, et al., at Carolinas Medical Center, recommended the antidote in very limited cases of severe acetaminophen toxicity, stating that they strongly believed that a single dose of fomepizole had a reasonable balance of potential benefit, safety, and cost to suggest its targeted use on a case-by-case basis until a randomized, controlled trial is performed

Agriculture 11 , 212 (2021)

For GI applications, some practitioners recommend oral administration to maximize local gastrointestinal exposure

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