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The plot shows the changes from before irradiation over a 24 hr period following a single dose of 10-Gy radiation in both CL1-0 and CL 1-5 cells

In this section, we provide an overview and discuss the mechanistic roles of SCFAs in the progression and prevention of neonatal diseases (Table 2)

Catharanthus roseus extract contains bioactive substances, including polyphenols acting as antioxidants

Future diagnostic strategies should prioritize the development and validation of multimodal biomarker panels that integrate complementary pathophysiological information from metabolic, inflammatory, and neurotrophic pathways, as such panels are expected to outperform single biomarkers in sensitivity, specificity, and their ability to guide personalized therapeutic interventions for DPN

10.1073/pnas.0709379104 4 AllenN