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It may also cause diarrhea

Deutsches Arzteblatt international, 106(34-35), pp

Without sufficient levels of this nutrient, people might experience bone pain and muscle weakness, and children could develop rickets, a condition leading to bone deformities

By reducing NNMT catalytic activity, the compound allows researchers to evaluate how limiting nicotinamide methylation influences: In vitro and in vivo experimental models (non-clinical, non-human) have demonstrated that NNMT suppression leads to measurable changes in cellular energy markers and adipocyte behavior