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MOTS-c activates AMPK (AMP-activated protein kinase), the master metabolic switch that signals cells to increase glucose uptake, accelerate fat oxidation, and promote mitochondrial biogenesis

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et al., 2019), miRNAs control mRNA expression, miRNAs are also capable of targeting non-coding RNAs, including long non-coding RNAs and miRNAs (Hill and Tran, 2021)