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Each member of the treatment groups in the scopolamine studies received an icy injection of scopolamine hydrobromide (70 nmol in 2 l aCSF over a duration of 20 s) 30 min prior to testing followed by Dihexa 10 min prior to testing

To prevent the contribution of dilution effects, metabolite data were mean-centered and the intensities of the spectral peaks of each given sample were normalized to the sum of all metabolite concentrations