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Decreased Appetite: Appetite suppression is expected and may aid in weight loss

Joints move with less pain

While vitamin B12 and folate can be taken together, you should not take too much folate when taking vitamin B12

These agents should not be used alone secondary to increases in plasma renin activity, cardiac output, and heart rate and should therefore be used only when -blockers and diuretics are part of the antihypertensive regimen