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However, the signal-to-noise from 13C-MRS is such that human studies generally require very large regions of interest and long acquisitions (over half of the frontal lobe for 120 min [139], contrasted with 5 to 10 min for single voxel 1 H-MRS and 17 min for EPSI)

10.1136/bmjopen-2018-025884 210 TenreiroL.AlvesS.AlvesP

Alpert LC, Schecter RL, Berry DA, et al

Results vary depending on metabolism, lifestyle, and skin condition, but generally: Consistency and professional supervision are key for optimal outcomes

For example, a Finnish/German tradition of sauna bathing is associated with lower incidence of colds and influenza