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Under specific immune microenvironment of the intestine, cytokines such as TGF- and IL-10 are abundant, which promote the differentiation of B cells into secretory IgA plasma cells, and the secreted IgA is transported into the intestinal lumen through IECs to control the invasion of intestinal bacteria by antibody neutralization (78, 79)

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Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases

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Increasing experimental data have recently shown that leptin is linked to the pathological and physiological processes of numerous mental illnesses and plays a vital regulatory role in the CNS