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In addition to increasing the likelihood of natural disasters (192), anthropogenic climate change has gradually led to environmental alterations, such as air pollution, loss of biodiversity, resource depletion, more frequent and heightened heatwaves, deforestation, and exacerbating water shortages, which may result in a wide range of health concerns, including instability and insecurity of resources, particularly food insecurity (180, 187, 188)

People with mild iron-deficiency anemia may not sense a problem while those with moderate to severe anemia can experience many symptoms, including: Tiredness or fatigue Weakness Headaches Pale or yellow skin Cold hands and feet Hair loss Irregular or fast heartbeat Chest pain Shortness of breath Dizziness or lightheadedness Pounding or whooshing sound in the ears Sore or smooth tongue Brittle nails Many of these symptoms can be innocuous and transient, or they could signal anemia or another health problem

A multiple imputation approach was used to handle missing data 31 , with imputation based on available data from participants in the same treatment arm with the same treatment status (on-treatment or discontinued)

Assessing the abuse potential of methylphenidate in nonhuman and human subjects: a review