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Edema Well-demarcated papules and nodules in affected area (may be pigmented) Most common in lower legs/ shins Shins Erythema Nodosum (pretibial area) Can affect feet, arms, elbows, face Thyroid Thyroid The thyroid gland is one of the largest endocrine glands in the human body

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Johnson R

In the field of biomarkers, the challenge extends beyond a simple lack of specificity to a more fundamental flaw in translational logic

J Pharmacol Exp Ther 255:529535 Fromenty B, Letteron P, Fisch C, Berson A, Deschamps D, Pessayre D (1993) Evaluation of human blood lymphocytes as a model to study the effects of drugs on human mitochondria

99, 2451246610.1021/cr980420v 120 WozniakK.BlasiakJ