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23 In a recent study, the serum levels of RANKL, OPG, and 8-hydroxy-2-deoxyguanosine as the marker of oxidative stress were measured to explore the implication of oxidative stress in bone metabolism based on the populations of healthy people and patients with osteoporosis, and the positive and independent correlation between increased oxidative stress markers and the subgroup of osteoporosis was found

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In the future, it is necessary to develop more effective reversal therapies, optimize early diagnostic methods, and advance personalized treatment strategies to improve patient outcomes and quality of life

Under chronic alcohol consumption the microsomal ethanol-oxidizing enzymeCYP2E1 is activated [67]

89 Consequently, intervention strategies targeting purine metabolism may hold potential for the treatment of ARDS patients