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Sample collection and neurochemical analysis On Day 16, after administration of the final treatment, all animals were euthanized using 95% CO2, and the brain was excised and weighed

The effects of Cagrilintide are usually evaluated through several factors: reduced food intake, fewer cravings, improved appetite control, longer satiety, and gradual weight reduction

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P62 is an autophagic receptor that directly inhibits Keap1 while promoting NRF2 activation (88)

ROS alters the redox status of the affected proteins through the oxidation of methionine residues and thiol groups in cysteine, which eventually influences the signalling processes