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Description

Pressure-dependent dysregulation of signaling mechanisms in anterior eye is reflected in aqueous humor composition, which shows altered levels of a striking number of signaling molecules that include adenosine, nitric oxide, ATP, endothelin-1 (ET-1), lipids (endocannabinoids, prostaglandins, cholesterol), transforming growth factor (TGF), CTGF (connective tissue growth factor), angiotensin II and cochlin