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the first lipid-containing conjugation partner is a compound of the formula (IIA-1): the second lipid-containing conjugation partner is a compound of the formula (IIB): L1 is C11-21alkyl k is 0-3, preferably 0 Ra, Rb, and Rc are each hydrogen

Importantly, the direction and magnitude of these expression changes are strongly context-dependent

Winden KD, Ebrahimi-Fakhari D, Sahin M

Although our study indicates the crotonylation of PGK1 at K131, K156, and K220 sites influences hypoxia-induced metabolic reprogramming, we cannot rule out the possibility that other lysine PTMs occurring at these three sites could also contribute to this process

A plethora of studies have shown that manipulating the gut microbiome leads to amelioration of frontoparietal and subcortical brain activity with cognitive function in minimal hepatic encephalopathic patients [255]