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While CagriSema showed somewhat similar results to Lillys Zepbound, it is also more complicated to manufacture, which analysts mentioned could be a potential pain point going forward

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A true answer would require a direct head-to-head study

The diagnosis of dementia was made according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.17 Only persons with a duration of symptoms longer than 6 months and a score for severity of dementia of 1 or higher on the Clinical Dementia Rating Scale were considered incident cases.18 Patients with suspected cognitive deficits for whom definite dementia could not be established underwent annual reassessment

Do not attempt to jump to a higher retatrutide dose based on prior cagrilintide experience