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Wirkstoff Sonstiges

[DOI] [PubMed] [Google Scholar] 138.Nemeth E, Tuttle MS, Powelson J, et al

HCAR1-mediated lactate effects have been suggested to be neuroprotective in depression (Tang et al., 2014

However, for both monotherapy of MEK inhibitor and combined treatment of BRAF and MEK inhibitors, acquired resistance through reactivation of the MAPK pathway can restrict their therapeutic efficacy (141)