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This raises an intriguing question of whether alternative sources of energy, such as ketone bodies by-passing the glycolytic pathway, might lead to increases in energy, and indeed some studies showed a reduction in fatigue in ME/CFS on a ketone diet [80]

A.RebbaaA.PampouS.WeisbergS

doi: 10.1128/AEM.03021-10 255 HegazySKEl-BedewyMM

Therapeutic implications: T1DM-associated metabolic insultsS1P depletion, glucolipotoxicityconverge on autophagic and epigenetic mechanisms to disable immunoregulatory cells