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However, in PD, abnormal iron accumulation in glial cells and dopaminergic neurons has been observed, with iron content strongly correlated with disease severity (249)

Mechanistically, ALA facilitated the phosphorylation of Akt, promoted the nuclear translocation of Nrf2, and augmented the expression of HO-1, while not influencing the activation of p38MAPK or the production of nitric oxide

Vitamin B12, as it is not biosynthesised without certain bacteria and algae must be taken with a diet

Formycin A (an analogue of adenosine) is a well-known inhibitor of hexameric PNPs (Bzowska et al

Urolithins: a comprehensive update on their metabolism, bioactivity, and associated gut microbiota