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Published 2023 Oct 29

First, it acted as a competitive inhibitor of 2-oxoglutarate-dependent dioxygenase (2-OGDD) function, and secondly, glutarate accumulation impaired activity of the pyruvate dehydrogenase complex (PDHc)

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Electroconvulsive therapy added to non-clozapine antipsychotic medication for treatment resistant schizophrenia: meta-analysis of randomized controlled trials