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Quantitative sensory testing reveals heightened temporal summation and diminished conditioned pain modulation in chronic pain conditions, indicating supraspinal mechanisms

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J Neurochem 79:959969 Kim HI, Raffler J, Lu W, Lee JJ, Abbey D, Saleheen D, Rabinowitz JD, Bennett MJ, Hand NJ, Brown C, Rader DJ (2017) Fine mapping and functional analysis reveal a role of SLC22A1 in acylcarnitine transport

The alteration of NMR spectra for CAR reflected these tendencies well

Image shows: Axial proton density weighted SPAIR MRI images from (a) before, (b) 12 months, and (c) 18 months into the intervention showing the hole within the proximal patellar tendon before the intervention and the progressive loss of signal at the inferior pole of the patella following the intervention